Menstrual Reduction With Extended Use of Combination Oral Contraceptive Pills: Randomized Controlled Trial

@article{Miller2001MenstrualRW,
  title={Menstrual Reduction With Extended Use of Combination Oral Contraceptive Pills: Randomized Controlled Trial},
  author={L. Miller and K. M. Notter},
  journal={Obstetrics & Gynecology},
  year={2001},
  volume={98},
  pages={771–778}
}
  • L. Miller, K. M. Notter
  • Published 2001
  • Medicine
  • Obstetrics & Gynecology
  • OBJECTIVE To compare a traditional 28‐day cycle to an extended 49‐day cycle of the 30 μg ethinyl estradiol (E2)/300 μg norgestrel monophasic birth control pill regimen. METHODS Ninety subjects randomized to either 28‐day cycles with 21 active pills or 49‐day cycles with 42 active pills for a prospective open label trial over four 84‐day reference periods or trimesters. Bleeding, pill taking, and symptom diaries were completed. The sample size with 80% power to detect a 40% reduction in bleeding… CONTINUE READING
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