Menopausal hormone use and endometrial cancer, by tumor grade and invasion.

@article{Shapiro1998MenopausalHU,
  title={Menopausal hormone use and endometrial cancer, by tumor grade and invasion.},
  author={Joel A. Shapiro and Noel S Weiss and Shirley A. A. Beresford and Lynda F. Voigt},
  journal={Epidemiology},
  year={1998},
  volume={9 1},
  pages={99-101}
}
We analyzed data from a population-based case-control study to investigate whether combined hormone replacement therapy influences the incidence of high-grade and -stage endometrial cancer. Subjects were women with epithelial endometrial cancer (N = 730) diagnosed during 1985-1991 and controls identified through random digit dialing (N = 1,002). Relative to hormone nonusers, women who took unopposed estrogens (mostly conjugated estrogens) for 3 or more years had a fivefold increase in the risk… CONTINUE READING