Menopausal hormone therapy: a better and safer future

  title={Menopausal hormone therapy: a better and safer future},
  author={D A Davey},
  pages={454 - 461}
  • D. Davey
  • Published 11 March 2018
  • Medicine
  • Climacteric
Abstract Major advances in menopause hormone therapy (MHT) hold promise in the future of better and safer care for women at and after the menopause. The principal advances are: (1) the critical window or ‘window of opportunity’ in the 10 years or so after the menopause, during which the benefits of MHT in healthy women exceed any risks; (2) use of transdermal instead of oral administration of estrogen to reduce the risk of venous thromboembolism; (c) investigation of the use of oral micronized… 

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Effects of oral and transdermal estrogen/progesterone regimens on blood coagulation and fibrinolysis in postmenopausal women. A randomized controlled trial.

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Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial.

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  • H. KuhlH. Schneider
  • Medicine, Biology
    Climacteric : the journal of the International Menopause Society
  • 2013
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High quality evidence is found that hormone therapy in both primary and secondary prevention conferred no protective effects for all-cause mortality, cardiovascular death, non-fatal myocardial infarction, angina, or revascularisation; the findings are dominated by the three largest trials.

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