Meniscal regeneration with copolymeric collagen scaffolds. In vitro and in vivo studies evaluated clinically, histologically, and biochemically.

@article{Stone1992MeniscalRW,
  title={Meniscal regeneration with copolymeric collagen scaffolds. In vitro and in vivo studies evaluated clinically, histologically, and biochemically.},
  author={Kevin R. Stone and William G. Rodkey and Richard J. Webber and L A McKinney and J. Richard Steadman},
  journal={The American journal of sports medicine},
  year={1992},
  volume={20 2},
  pages={104-11}
}
We sought to create a regeneration template for the meniscal cartilage of the knee to induce complete meniscal regeneration, and to develop the technique for implanting the prosthetic appliance in vivo. We designed a resorbable collagen-based scaffold and conducted in vitro and in vivo studies. In vivo, the scaffold was implanted in the knees of immature swine and mature canines and evaluated clinically, histologically, and biochemically. Because the canine stifle joint meniscus is more… CONTINUE READING

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