Meningococcal disease: the advances and challenges of meningococcal disease prevention.

@article{Yogev2011MeningococcalDT,
  title={Meningococcal disease: the advances and challenges of meningococcal disease prevention.},
  author={Ram Yogev and Tina Q. Tan},
  journal={Human vaccines},
  year={2011},
  volume={7 8},
  pages={828-37}
}
Vaccination as a means to prevent meningococcal disease caused by Neisseria meningitidis is critical given the abrupt onset and rapid progression of this disease. Five serogroups--A, B, C, W-135, and Y--are responsible for the majority of cases. In developed countries, infants have the greatest risk of disease, with a smaller secondary peak observed in late adolescence. Vaccines utilizing the polysaccharide capsule are poorly immunogenic in young children but can reduce the incidence of… CONTINUE READING
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