Meniere’s disease

  title={Meniere’s disease},
  author={John A. Harcourt and Kevin Barraclough and Adolfo M Bronstein},
  journal={BMJ : British Medical Journal},
#### The bottom line Meniere’s disease is often considered in the differential diagnosis of episodic dizziness, although it is not a common cause of new onset vertigo. Rather it is a disorder of the inner ear, characterised by recurrent attacks of self limiting vertigo. These attacks are associated with unilateral fluctuating low frequency sensorineural hearing loss, a sense of “fullness” in the affected ear (aural fullness), and tinnitus.1 Clinical findings are initially normal between… 
Ménière’s disease and chronic cerebrovascular diseases
  • V. Parfenov
  • Medicine
    Meditsinskiy sovet = Medical Council
  • 2021
Diagnostic errors are usually caused by the fact that the patients with MD are not conducted audiometry, vestibular tests, and the signs of cerebral microangiopathy identified when MRI brain are mistakenly regarded as confirmation of vascular dizziness genesis.
Pharmacologic and surgical therapies for patients with Meniere’s disease: a protocol for a systematic review and meta-analysis
A planned systematic review of existing treatments for management of Meniere’s disease will inform practitioners as to the relative benefits and harms of the existing competing interventions, offer optimal clinical treatment strategies, identify evidence gaps, and determine promising therapies for evaluation in future trials.
Intratympanically administered steroid for progressive sensorineural hearing loss in Ménière’s disease
Intratympanically administered dexamethasone is a potent agent to prevent the progression of hearing loss in MD and there was a strong correlation between hearing improvement and dexamETHasone treatment.
Dizziness: Approach to Evaluation and Management.
Evaluation focuses on determining whether the etiology is peripheral or central, and the HINTS (head-impulse, nystagmus, test of skew) examination can help distinguish peripheral from central etiologies.
Restriction of salt, caffeine and alcohol intake for the treatment of Ménière's disease or syndrome.
There is no evidence from randomised controlled trials to support or refute the restriction of salt, caffeine or alcohol intake in patients with Ménière's disease or syndrome.
State of the Art Imaging in Menière’s Disease. Tips and Tricks for Protocol and Interpretation
Delayed contrast enhanced MRI has emerged as a reliable technique to demonstrate endolymphatic hydrops in vivo, with promising application in the diagnosis and follow-up of MD patients.
Aural fullness and transtympanic ventilation tubes in Ménière's disease: a scoping review
There is a paucity of evidence investigating the effect of grommet insertion on aural fullness in Ménière's disease, and this work directs future research into this topic.
Wideband tympanometry as a diagnostic tool for Meniere’s disease: a retrospective case-control study
The results indicate that WBT potentially could be a useful and simple non-invasive diagnostic tool for Ménière’s disease by comparing differences in absorbance measures between normal hearing ears and patient diagnosed with MD.


Diuretics for Ménière's disease or syndrome.
There is insufficient good evidence of the effect of diuretics on vertigo, hearing loss, tinnitus or aural fullness in clearly defined Ménière's disease.
Natural History vs. Surgery for Meniere's Disease
It is indicated statistically that the ELS procedure does not alter the long-term natural course of vertigo control in Meniere's disease, whereas both the RVN and CVN significantly improve the patient's chance of being permanently free of Vertigo attacks.
Characteristics of six otologic diseases involving vertigo.
  • E. Kentala
  • Medicine
    The American journal of otology
  • 1996
The most severe forms of vertigo and nausea were found in vestibular neuritis, whereas the most severe case of tinnitus appeared in Meniere's disease, and factorial analysis did not aid the clustering of these diseases.
Betahistine for Menière's disease or syndrome.
No trial met the highest quality standard set by the review because of inadequate diagnostic criteria or methods, and none assessed the effect of betahistine on vertigo adequately, so there is insufficient evidence to say whether bethistine has any effect on Menière's disease.
Drop attacks in Menière's disease.
Twenty-nine patients with frequent and severe Meniere attacks were treated with gentamicin intratympanally, when they had reached a stage of incapacitation due to vertigo and dread of further attacks and all medical treatments had failed.
Approach to the dizzy patient.
  • R. Baloh
  • Medicine, Biology
    Bailliere's clinical neurology
  • 1994
The treatment strategy for an acute peripheral vestibular lesion has evolved over the past few years and probably the most important treatment breakthrough is the positional manoeuvre that reliably cures benign positional vertigo.
Outcomes of Intratympanic Gentamicin Injection to Treat Ménière’s Disease
  • L. Huon, Te-Yung Fang, Pa-Chun Wang
  • Medicine
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • 2012
A critical literature appraisal and meta-analysis shows that IT gentamicin injection can control vertigo in patients with MD who have limited hearing injury.
Current-Day Prevalence of Ménière’s Syndrome
To assess the current-day prevalence of MS in the US, data from a medical and pharmaceutical claims database containing information for over 60 million unique patients were analyzed and a 3-year period from 2005 to 2007 was analyzed.
Placebo effect in surgery for Menière's disease. A double-blind placebo-controlled study on endolymphatic sac shunt surgery.
Minor differences were seen between active and placebo groups, but the greatest difference in symptoms was found when preoperative and postoperative scores were compared: both groups improved significantly.
Long-Term Follow up of 610 Cases of Ménière's Disease
The aim of this paper is to discuss some of the statistical findings which have arisen from the study of the clinical records of patients suffering from Meniere's disease, in some of whom the follow