Mendelian and uniparental alterations in erythromycin binding by plastid ribosomes.

@article{Mets1971MendelianAU,
  title={Mendelian and uniparental alterations in erythromycin binding by plastid ribosomes.},
  author={Laurens J. Mets and L. Bogorad},
  journal={Science},
  year={1971},
  volume={174 4010},
  pages={
          707-9
        }
}
Erythromycin binds specifically to the 52S subunit of the chloroplast ribosome of Chlamydomonas reinhardi. A number of erythromycin-resistant mutants whose ribosomes have lost their affinity for the antibiotic have been isolated, but the sedimentation properties of their ribosomes are indistinguishable from those of the wild-type strain. These mutants represent at least three genetic loci. Two of them show Mendelian inheritance, and one of them is inherited in a uniparental manner. 

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