Menatetrenone ameliorates osteopenia in disuse-affected limbs of vitamin D- and K-deficient stroke patients.

@article{Sato1998MenatetrenoneAO,
  title={Menatetrenone ameliorates osteopenia in disuse-affected limbs of vitamin D- and K-deficient stroke patients.},
  author={Yoshihiro Sato and Yoshiaki Honda and H Kuno and Kotaro Oizumi},
  journal={Bone},
  year={1998},
  volume={23 3},
  pages={291-6}
}
Significant reduction in bone mineral density (BMD) occurs in stroke patients on the hemiplegic and contralateral sides, correlating with the degree of paralysis and vitamin D and K deficiency due to malnutrition, and increasing the risk of hip fracture. We evaluated the efficacy of vitamin K2 (menatetrenone: menaquinone-4; MK-4) in maintaining BMD by comparing serum biochemical indices of bone metabolism between treated and untreated patients. In a random and prospective study, of 108… CONTINUE READING

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