Memory retrieval improvement by Ptychopetalum olacoides in young and aging mice.

@article{Silva2004MemoryRI,
  title={Memory retrieval improvement by Ptychopetalum olacoides in young and aging mice.},
  author={Adriana Lourenço da Silva and Angelo L S Piato and Simone Bardini and Carlos Alexandre Netto and Domingos S{\'a}vio Nunes and Elaine Elisabetsky},
  journal={Journal of ethnopharmacology},
  year={2004},
  volume={95 2-3},
  pages={199-203}
}
Amazonian peoples use traditional remedies prepared with Ptychopetalum olacoides (PO) roots for treating various age-related conditions. This study shows that a single intraperitoneally (i.p.) administration of Ptychopetalum olacoides ethanol extract (POEE, 50 and 100mg/kg) improved memory retrieval in step-down inhibitory avoidance (P <or= 0.05 and P <or= 0.01, test session latency 102 [19.38-300] and 192 [91.3-300]s, respectively versus control 24.7 [12.9-89.6]), without interfering with… CONTINUE READING

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