Memory reactivation in healthy aging: evidence of stimulus-specific dedifferentiation.

@article{StLaurent2014MemoryRI,
  title={Memory reactivation in healthy aging: evidence of stimulus-specific dedifferentiation.},
  author={Marie St-Laurent and Herv{\'e} Abdi and Ashley Bondad and Bradley R. Buchsbaum},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2014},
  volume={34 12},
  pages={4175-86}
}
We investigated how aging affects the neural specificity of mental replay, the act of conjuring up past experiences in one's mind. We used functional magnetic resonance imaging (fMRI) and multivariate pattern analysis to quantify the similarity between brain activity elicited by the perception and memory of complex multimodal stimuli. Young and older human adults viewed and mentally replayed short videos from long-term memory while undergoing fMRI. We identified a wide array of cortical regions… CONTINUE READING
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