Memory impairment in chronic pain patients and the related neuropsychological mechanisms: a review

  title={Memory impairment in chronic pain patients and the related neuropsychological mechanisms: a review},
  author={Xianhua Liu and Li Li and Fang-Gui Tang and Siwei Wu and Yiqiu Hu},
  journal={Acta Neuropsychiatrica},
  pages={195 - 201}
Objective This study provides a comprehensive review of the literature on memory impairment and the potential effective factors in patients with chronic pain. Methods A literature search of databases PubMed, EMBASE, SpringerLink, and PsycINFO until September 2012 was conducted using the keywords ‘memory’ and ‘chronic pain’. The study emphasises on publications over the past 20 years. Results Memory impairment in chronic pain patients is substantial, but the aspects of memory (e.g. working… 

Mediating effects of working memory on the relationship between chronic pain and overgeneral autobiographical memory

It is suggested that WM and AM are impaired in the patients with chronic pain, and WM acts an important mediating role between chronic pain and OGM.

Chronic pain in osteoarthritis of the hip is associated with selective cognitive impairment

Chronic pain secondary to end-stage hip OA is associated with selective cognitive impairment and future studies are required to investigate the effect of total hip arthroplasty on cognitive performance.

Insomnia-related Memory Impairment in Individuals With Very Complex Chronic Pain

Intervention of insomnia may possibly explain some of the cognitive impairments related to chronic pain; thus, screening for, and treating, sleep disturbances may be a central aspect of chronic pain rehabilitation.

Impact of Pain on Cognitive Function in Forensic Neuropsychology Context

Chronic pain is a biopsychosocial condition with a complex neuroscientific and neuropsychological literature. Common types of pain that are seen in the medicolegal context include headaches and

Impaired psychomotor ability and attention in patients with persistent pain: a cross-sectional comparative study

Persistent musculoskeletal pain seems to impair performance on a wider range of cognitive tasks than acute or regularly recurrent pain, using pain-free individuals as a benchmark; however, there is some evidence of impairment in psychomotor ability among patients with acute pain and some impairment in sustained attention among Patients with regularly recurrentPain.

Cognitive deficits in chronic pain patients, in a brief screening test, are independent of comorbidities and medication use.

Patients with chronic pain showed a poorer performance in a brief screening test for cognitive impairment not related to confounding variables, as comorbidities and pain-medication use.

Cognitive Effects and Sedation.

CES is prevalent in chronic nonmalignant pain populations receiving long-term opioid therapy and are among the most common reasons patients discontinue opioid use, particularly among the elderly.

Psychological Factors Associated with Phantom Limb Pain: A Review of Recent Findings

Research on the role of emotional, motivational, cognitive, and perceptual factors in phantom limb pain indicates that emotional factors modulate PLP but might be less important compared to other types of chronic pain.

Cannabis Use and Cognition in Adults Prescribed Opioids for Persistent Pain.

Risk factors for neurocognitive impairment in patients with benign intracranial lesions

Age and KPS are the main risk factors for poorer neurocognitive functions in the category attention in patients with benign intracranial lesions and knowledge of these risk factors might be important to find appropriate therapy regimes to improve cognitive functions and quality of life.



Memory Functions in Chronic Pain: Examining Contributions of Attention and Age to Test Performance

It is indicated that chronic pain significantly affects memory performance, and part of this effect may be caused by underlying attentional dysfunction, although this could not fully explain the observed memory decline.

Memory Complaints in Chronic Pain

The findings suggest that memory complaints are higher in patients with chronic pain than in medical/dental or psychotherapy patients and not only to depression but also to the presence of chronic pain.

Reports of Memory Functioning by Patients With Chronic Pain

The hypothesis that emotional distress (depression and anxiety) plays an important role in memory complaints in patients with chronic pain, as well as rumination, the intrusive component of catastrophizing, is supported.

Evidences of memory dysfunction and maladaptive coping in chronic low back pain and rheumatoid arthritis patients: challenges for rehabilitation.

By analyzing memory deficits of chronic pain patients, clinicians could establish targeted rehabilitation programs and outcomes by analyzing memory scores and coping skills, as a disability evaluation measure.

Disruption of Attention and Working Memory Traces in Individuals with Chronic Pain

Findings point to a specific cognitive mechanism, the maintenance of the memory trace, that is affected by chronic pain during task performance, and Cognitive function was not improved by short-term local analgesia.

Phantom headache: pain-memory-emotion hypothesis for chronic daily headache?

It is speculated that pain, memory, and emotions are interrelated in triangular pattern, and each of these three is related to other two in bidirectional pattern, i.e., stimulation of one of these will stimulate other symptoms/networks and vice versa (triangular theory for chronic pain).

Pain, malingering and the WAIS-III Working Memory Index.

Predicting complaints of impaired cognitive functioning in patients with chronic pain.

Memory distortion during acute and chronic pain recalling.

Pain memory distorsion is related to pain intensity variation during treatment rather than present pain, and it is inversely related to the initial pain intensity, so it is not correct to evaluate pain relief at the end of treatment since this procedure can under- or over-estimate theInitial pain.