Memory function in very early Alzheimer's disease.

  title={Memory function in very early Alzheimer's disease.},
  author={Ronald C. Petersen and Glenn E. Smith and Robert J. Ivnik and Emre Kokmen and Eric G. Tangalos},
  volume={44 5},
The detection of very early Alzheimer's disease (AD) can be important for both theoretical and practical reasons. Typically, a memory impairment is the first sign of incipient disease, but the early clinical diagnosis can be challenging. We investigated several aspects of memory function in AD and normal aging to determine which indices of performance were most sensitive at detecting early impairments. We evaluated 106 pairs of patients with probable AD and matched controls from the Mayo Clinic… CONTINUE READING