Memory for places learned long ago is intact after hippocampal damage
@article{Teng1999MemoryFP, title={Memory for places learned long ago is intact after hippocampal damage}, author={Edmond Teng and Larry R. Squire}, journal={Nature}, year={1999}, volume={400}, pages={675-677} }
The hippocampus is part of a system of structures in the medial temporal lobe that are essential for memory. One influential view of hippocampal function emphasizes its role in the acquisition and retrieval of spatial knowledge,. By this view, the hippocampus constructs and stores spatial maps and is therefore essential for learning and remembering places, including those learned about long ago. We tested a profoundly amnesic patient (E.P.), who has virtually complete bilateral damage to the…
372 Citations
Remote spatial memory in an amnesic person with extensive bilateral hippocampal lesions
- Psychology, BiologyNature Neuroscience
- 2000
Remote spatial memory in K.C, a patient with bilateral hippocampal lesions and amnesia for autobiographical events, suggests that the hippocampus is not crucial for maintenance and retrieval of remotely formed spatial representations of major landmarks, routes, distances and directions, but is necessary for specifying location details, regardless of when they were acquired.
Memory for familiar environments learned in the remote past: fMRI studies of healthy people and an amnesic person with extensive bilateral hippocampal lesions
- Biology, PsychologyHippocampus
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The distinction between recent and remote memory may apply as much to spatial theories of hippocampal function as it does to theories emphasizing the role of the hippocampus in other types of explicit memory.
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- Psychology, BiologyProceedings of the National Academy of Sciences
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It is suggested that the hippocampus is not needed to carry out the spatial computations needed for map reading and navigating from maps, and the impairment in map reading associated with large MTL lesions may depend on damage in or near the parahippocampal cortex.
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- Biology, Psychology
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The findings show that memory processing and consolidation require a time-dependent hippocampal-cortical dialogue, ultimately enabling structured cortical networks to mediate recall and use of cortically stored remote memories independently.
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- Biology, Psychology
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A coherent view of what makes a task hippocampallydependent at acquisition and how this relates to its long-term fate is formulated and conceptualising episodic and semantic memory as representing points on a continuum of memory types appears viable.
Impaired remote spatial memory after hippocampal lesions despite extensive training beginning early in life
- Psychology, BiologyHippocampus
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Even after extended training beginning early in life, and with a prolonged training–surgery interval, hippocampal lesions impair performance in the water maze task.
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- Biology, PsychologyHippocampus
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Animal studies support the notion that information is stored in both hippocampal and extrahipocampal sites, and that retrieval from different sites involves access to different kinds of information, and help to explain why graded retrograde amnesia is sometimes seen after brain damage.
Hippocampal area CA1 and remote memory in rats.
- Psychology, BiologyLearning & memory
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A discrete lesion targeting area CA1, the sole output of the hippocampus to neocortex, was developed and tested the effects of this lesion on recent and remote memory in the watermaze task, in context fear conditioning, and in trace fear conditioning; in all three tasks, recent andRemote memory were similarly impaired after CA1 lesions.
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- Psychology, Biology
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The role of the human hippocampus in spatial and episodic memory was investigated using methods from neuropsychology, experimental psychology and functional magnetic resonance imaging, and the relationship between viewpoint independence, multi-modal context and semantic embedding in retrieval was discussed.
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