Memory erasure by very high concentrations of ZIP may not be due to PKM-zeta.

@article{Lisman2012MemoryEB,
  title={Memory erasure by very high concentrations of ZIP may not be due to PKM-zeta.},
  author={John Lisman},
  journal={Hippocampus},
  year={2012},
  volume={22 3},
  pages={648-9}
}
The molecular basis of memory at synapses is one of the major outstanding problems in neuroscience. The article of Pastalkova et al. (2006), and subsequent articles based on their methods, makes the strong claim that memory maintenance (i.e., storage) is due to the protein kinase, PKM-zeta. In support of this, Pastalkova et al. performed the key tests of any model of memory maintenance: whether inhibition of the putative memory molecule can erase previously induced long-term potentiation (LTP… CONTINUE READING
Highly Cited
This paper has 204 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

1 Figure or Table

Topics

Statistics

0501001502012201320142015201620172018
Citations per Year

204 Citations

Semantic Scholar estimates that this publication has 204 citations based on the available data.

See our FAQ for additional information.