Memory enhancing effects of granisetron (BRL 43694) in a passive avoidance task.

@article{Chugh1991MemoryEE,
  title={Memory enhancing effects of granisetron (BRL 43694) in a passive avoidance task.},
  author={Yati Chugh and N. K. Saha and Aruna Sankaranarayanan and Pooja Sharma},
  journal={European journal of pharmacology},
  year={1991},
  volume={203 1},
  pages={121-3}
}
Recent evidence suggests that serotonin plays an important role in learning and memory processes in animals. The present study examined the effect of the 5-HT3 receptor antagonist, granisetron (BRL 43694), on acquisition, retention and retrieval of a passive avoidance response in mice. Granisetron (1 and 10 micrograms/kg) administered 30 min before presentation of footshock increased the step-down latency when tested 24 h after footshock. The acquisition process was not affected by a dose of… CONTINUE READING

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