Memory-contingent saccades and the substantia nigra postulate for essential blepharospasm.

@article{Hotson1991MemorycontingentSA,
  title={Memory-contingent saccades and the substantia nigra postulate for essential blepharospasm.},
  author={John R. Hotson and D R Boman},
  journal={Brain : a journal of neurology},
  year={1991},
  volume={114 ( Pt 1A)},
  pages={295-307}
}
Essential blepharospasm and cranial dystonia are related focal dystonias of unknown aetiology. Blepharospasm induced by acute dopamine depletion in parkinsonism restricts saccade initiation possibly via the substantia nigra pars reticulata (SNpr). If essential blepharospasm and cranial dystonia similarly restrict saccades, then a selective, somatotopically arranged pathway such as the SNpr may be involved. To test this possibility memory-contingent and visually-guided saccades were measured in… CONTINUE READING