Memory consolidation and the amygdala: a systems perspective

@article{McGaugh2002MemoryCA,
  title={Memory consolidation and the amygdala: a systems perspective},
  author={J. D. McGaugh},
  journal={Trends in Neurosciences},
  year={2002},
  volume={25},
  pages={456-461}
}
  • J. D. McGaugh
  • Published 1 September 2002
  • Biology, Psychology
  • Trends in Neurosciences
3.26 – Memory Modulation
The amygdala modulates the consolidation of memories of emotionally arousing experiences.
  • J. D. McGaugh
  • Biology, Psychology
    Annual review of neuroscience
  • 2004
TLDR
Findings from animal and human studies indicate that the amygdala mediates the memory-modulating effects of adrenal stress hormones and several classes of neurotransmitters and plays a key role in enabling emotionally significant experiences to be well remembered.
Role of the basolateral amygdala in memory consolidation
  • D. Paré
  • Biology, Psychology
    Progress in Neurobiology
  • 2003
Glucocorticoid Effects on Memory Consolidation Depend on Functional Interactions between the Medial Prefrontal Cortex and Basolateral Amygdala
TLDR
Findings indicate that glucocorticoid effects on memory consolidation depend on bidirectional interactions between the BLA and the medial prefrontal cortex, a brain region involved in higher-order cognitive and affective processing.
Differential involvement of the hippocampus, anterior cingulate cortex, and basolateral amygdala in memory for context and footshock.
TLDR
Evidence that the hippocampus and rACC play selective roles in memory for specific components of training experiences is consistent with evidence that the BLA is more liberally involved in modulating memory consolidation for various aspects of emotionally arousing experiences.
Glucocorticoids in the prefrontal cortex enhance memory consolidation and impair working memory by a common neural mechanism
TLDR
Findings provide direct evidence that glucocorticoid effects on both memory consolidation and working memory share a common neural influence within the medial prefrontal cortex of male Sprague-Dawley rats.
Emotional Modulation of Learning and Memory: Pharmacological Implications
TLDR
This review considers the historical understanding for memory modulation and cellular consolidation processes and examines several research areas currently using this foundational knowledge to develop therapeutic treatments.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 95 REFERENCES
Basolateral Amygdala–Nucleus Accumbens Interactions in Mediating Glucocorticoid Enhancement of Memory Consolidation
TLDR
The present experiments indicate that the BLA–NAc pathway plays an essential role in mediating glucocorticoid effects on memory consolidation and suggest that theBLA interacts with hippocampal effects onMemory consolidation via this pathway.
Amygdala circuitry in attentional and representational processes
Microinfusions of Flumazenil into the Basolateral but Not the Central Nucleus of the Amygdala Enhance Memory Consolidation in Rats
TLDR
Findings indicate that the BLA is selectively involved in mediating flumazenil's influence on memory storage and are consistent with extensive evidence indicating that theBLA is involved in regulating memory consolidation.
Memory formation: evidence for a specific neurochemical system in the amygdala.
TLDR
The results support a role for an amygdala beta-adrenergic system in memory processes and time-dependent and dose-dependent decreases in retention of the task.
Parallels between cerebellum- and amygdala-dependent conditioning
Recent evidence from cerebellum-dependent motor learning and amygdala-dependent fear conditioning indicates that, despite being mediated by different brain systems, these forms of learning might use
Lesions of the nucleus basalis magnocellularis induced by 192 IgG-saporin block memory enhancement with posttraining norepinephrine in the basolateral amygdala
TLDR
It is found that cholinergic NBM-cortex projections are required for BLA-mediated modulation of memory consolidation and are implicated in learning, memory storage, and plasticity.
Involvement of a basolateral amygdala complex–nucleus accumbens pathway in glucocorticoid‐induced modulation of memory consolidation
TLDR
Findings indicate that an intact BLC–NA pathway is critical for the enhancing effects of glucocorticoids on memory consolidation, and are consistent with the view that the BLC regulates memory consolidation in other brain regions.
...
1
2
3
4
5
...