Memory consolidation, retrograde amnesia and the hippocampal complex

@article{Nadel1997MemoryCR,
  title={Memory consolidation, retrograde amnesia and the hippocampal complex},
  author={Lynn Nadel and Morris Moscovitch},
  journal={Current Opinion in Neurobiology},
  year={1997},
  volume={7},
  pages={217-227}
}
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References

SHOWING 1-10 OF 103 REFERENCES
Retrograde amnesia and memory consolidation: a neurobiological perspective
The medial temporal lobe memory system
TLDR
The medial temporal lobe memory system is needed to bind together the distributed storage sites in neocortex that represent a whole memory, but the role of this system is only temporary, as time passes after learning, memory stored in neoc cortex gradually becomes independent of medialporal lobe structures.
Which brain regions are critically involved in the retrieval of old episodic memory?
Different degrees of impairment in anterograde retrograde memory and recall/recognition performance in a transient global amnesic case
Abstract A 59-year-old patient with transient global amnesia was tested neuropsychologically during and after the attack. During the attack the patient manifested major problems with anterograde, but…
Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus
TLDR
This is the first reported case of amnesia following a lesion limited to the hippocampus in which extensive neuropsychological and neuropathological analyses have been carried out.
Frontal lobes and the temporal organization of memory.
TLDR
It has now been established that the frontal cortex participates in judgements of the temporal order of recent events and of their frequency of occurrence, as well as in the planning and monitoring of the execution of self-determined sequences of responses.
Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans.
  • L. Squire
  • Biology, Psychology
    Psychological review
  • 1992
TLDR
The role of the hippocampus is considered, which is needed temporarily to bind together distributed sites in neocortex that together represent a whole memory.
Memory, amnesia, and frontal lobe dysfunction
TLDR
Evidence concerning the influence of frontal lobe pathology on amnesic disorders is reviewed, different interpretations of this evidence are discussed, and research from human and animal neuropsychology as well as cognitive psychology is drawn on in an attempt to clarify the role of frontal damage in the amnesi syndrome.
Differentiating the roles of the hippocampal complex and the neocortex in long-term memory storage: evidence from the study of semantic dementia and Alzheimer's disease.
TLDR
It is demonstrated that patients with semantic dementia, who have relative sparing of the hippocampal complex, show a pattern of preserved recent memories and impaired distant memories.
Loss of remote memory: a cognitive neuropsychological perspective
...
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