Memory complaints and increased rates of brain atrophy: risk factors for mild cognitive impairment and Alzheimer's disease.

@article{Archer2010MemoryCA,
  title={Memory complaints and increased rates of brain atrophy: risk factors for mild cognitive impairment and Alzheimer's disease.},
  author={Hilary A. Archer and John Kennedy and Josephine Barnes and T. Pepple and Richard Boyes and Katy Randlesome and Shona Clegg and Kelvin K. Leung and S{\'e}bastien Ourselin and Chris Frost and Martin Rossor and Nick C. Fox},
  journal={International journal of geriatric psychiatry},
  year={2010},
  volume={25 11},
  pages={1119-26}
}
AIM To determine rates of cerebral atrophy in individuals with symptoms of memory loss but no objective cognitive impairment (SNCI) and their association with future cognitive decline. METHODS Thirty-two SNCI subjects, 16 with mild cognitive impairment (MCI) and 27 control subjects had clinical assessment and magnetic resonance imaging at baseline and 1 year later. Rates of whole brain atrophy (WBA), hippocampal atrophy (HA) and ventricular enlargement (VE) were measured. Our outcome was… CONTINUE READING