Memory CD8 T Cells Specific for Plasmodia Liver-Stage Antigens Maintain Protracted Protection Against Malaria

@inproceedings{Krzych2012MemoryCT,
  title={Memory CD8 T Cells Specific for Plasmodia Liver-Stage Antigens Maintain Protracted Protection Against Malaria},
  author={Urszula Krzych and Sarat Kumar Dalai and Stasya Zarling and Alexander Pichugin},
  booktitle={Front. Immun.},
  year={2012}
}
Immunologic memory induced by pathogenic agents or vaccinations is inextricably linked to long-lasting protection. Adequately maintained memory T and B cell pools assure a fast, effective, and specific response against re-infections. Studies of immune responses amongst residents of malaria endemic areas suggest that memory responses to Plasmodia antigens appear to be neither adequately developed nor maintained, because persons who survive episodes of childhood malaria remain vulnerable to… CONTINUE READING
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Long term protection after immunization with P

  • K. Nganou-Makamdop, G. J. Van Gemert, T. Arens, C. C. Hermsen, R. W. Sauerwein
  • berghei sporozoites corre-
  • 2012
Highly Influential
8 Excerpts

IL - 15 maintains a reservoir of central memory CD 8 T cells that are required for protracted protection against Plasmodium berghei infection

  • U. Krzych, N. Steers, J. Lumsden, D. Berenzon, D. Liepinsh, R. Schwenk
  • Am . J . Trop . Med . Hyg .
  • 2009
Highly Influential
4 Excerpts

tracted protection to Plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory CD 8 + T cells

  • D. Berenzon, R. J. Schwenk, M. Guebre-Xabier, J. Williams, U. Krzych
  • J . Immunol .
  • 2003
Highly Influential
15 Excerpts

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