Memory B cells and CD27.

  title={Memory B cells and CD27.},
  author={Kazunaga Agematsu},
  journal={Histology and histopathology},
  volume={15 2},
Following antigen activation in germinal centers, B cells develop into memory B cells or plasma cells. Triggering via B-cell immunoglobulin receptors by antigens, cytokines and direct cell-to-cell contact by B and T cells plays an important role in the B cell differentiation into memory or plasma cells. Adult human peripheral blood B cells are separated into three subtypes by the expression of IgD and CD27, which belong to the tumor necrosis factor receptor (TNFR) family: IgD+ CD27- naive B… CONTINUE READING