Memory--a century of consolidation.
@article{McGaugh2000MemoryaCO, title={Memory--a century of consolidation.}, author={J. D. McGaugh}, journal={Science}, year={2000}, volume={287 5451}, pages={ 248-51 } }
The memory consolidation hypothesis proposed 100 years ago by Müller and Pilzecker continues to guide memory research. The hypothesis that new memories consolidate slowly over time has stimulated studies revealing the hormonal and neural influences regulating memory consolidation, as well as molecular and cellular mechanisms. This review examines the progress made over the century in understanding the time-dependent processes that create our lasting memories.
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Commentary — reconsolidation: Memory traces revisited
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- 2000
The implications of these and earlier findings to the understanding of consolidation are commented on, and their possible relationship to the idea that retrieval creates a new memory trace, increasing the resistance of older memories to disruption is explored.
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Molecular mechanisms of memory acquisition, consolidation and retrieval
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Molecular stepping stones in memory consolidation
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Antisense against the transcription factor C/EBPβ in the hippocampus is now reported to disrupt the initial consolidation of memories, but not their 'reconsolidation' after later recall.
Systems-Level Reconsolidation Reengagement of the Hippocampus with Memory Reactivation
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- 2019
This doctoral thesis aims to track episodic memory reactivation during consolidation and retrieval by means of its oscillatory signatures and uncovers how their underlying neural mechanisms unfold over time and space to coordinate behaviour.
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