Membranoproliferative glomerulonephritis type II (dense deposit disease): an update.
@article{Appel2005MembranoproliferativeGT, title={Membranoproliferative glomerulonephritis type II (dense deposit disease): an update.}, author={G. Appel and H. Cook and G. Hageman and J. Jennette and M. Kashgarian and M. Kirschfink and J. Lambris and Lynne Lanning and H. Lutz and S. Meri and N. Rose and D. Salant and S. Sethi and R. Smith and W. Smoyer and Hope F Tully and Sean P Tully and P. Walker and M. Welsh and R. W{\"u}rzner and P. Zipfel}, journal={Journal of the American Society of Nephrology : JASN}, year={2005}, volume={16 5}, pages={ 1392-403 } }
Membranoproliferative glomerulonephritis type II (MPGN II) is a rare disease characterized by the deposition of abnormal electron-dense material within the glomerular basement membrane of the kidney and often within Bruch's membrane in the eye. The diagnosis is made in most patients between the ages of 5 and 15 yr, and within 10 yr, approximately half progress to end-stage renal disease, occasionally with the late comorbidity of visual impairment. The pathophysiologic basis of MPGN II is… Expand
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