Membranoproliferative glomerulonephritis in a patient with X-linked agammaglobulinemia

  title={Membranoproliferative glomerulonephritis in a patient with X-linked agammaglobulinemia},
  author={Atsunori Yoshino and Masataka Honda and Hirokazu Kanegane and Kazuo Obata and Hiroyoshi Matsukura and Satoru Sakazume and Yasuki Katada and Toshio Miyawaki and Yoshihiko Ueda and Toshiro Nagai},
  journal={Pediatric Nephrology},
Immune complex and complement systems play an important role in membranoproliferative glomerulonephritis (MPGN). X-linked agammaglobulinemia (XLA) is a primary immunodeficiency characterized by severe hypogammaglobulinemia. We report the case of an XLA patient who developed MPGN during an intravenous immunoglobulin (IVIG) treatment. In this patient, the serum IgG level was maintained at more than 400 mg/dl of regular IVIG administration (2.5 g/dose/month). The patient presented with microscopic… CONTINUE READING
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