Membrane transporters in the relict plastid of malaria parasites.

@article{Mullin2006MembraneTI,
  title={Membrane transporters in the relict plastid of malaria parasites.},
  author={Kylie A. Mullin and Liting Lim and Stuart A. Ralph and Timothy P Spurck and Emanuela Handman and Geoffrey Ian McFadden},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 25},
  pages={9572-7}
}
Malaria parasites contain a nonphotosynthetic plastid homologous to chloroplasts of plants. The parasite plastid synthesizes fatty acids, heme, iron sulfur clusters and isoprenoid precursors and is indispensable, making it an attractive target for antiparasite drugs. How parasite plastid biosynthetic pathways are fuelled in the absence of photosynthetic capture of energy and carbon was not clear. Here, we describe a pair of parasite transporter proteins, PfiTPT and PfoTPT, that are homologues… CONTINUE READING
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