Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues.

@article{Zhao2009MembraneTA,
  title={Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues.},
  author={Rongbao Zhao and Larry H. Matherly and I. David Goldman},
  journal={Expert reviews in molecular medicine},
  year={2009},
  volume={11},
  pages={e4}
}
Members of the family of B9 vitamins are commonly known as folates. They are derived entirely from dietary sources and are key one-carbon donors required for de novo nucleotide and methionine synthesis. These highly hydrophilic molecules use several genetically distinct and functionally diverse transport systems to enter cells: the reduced folate carrier, the proton-coupled folate transporter and the folate receptors. Each plays a unique role in mediating folate transport across epithelia and… CONTINUE READING
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