Membrane transport of long-chain fatty acids: evidence for a facilitated process.

  title={Membrane transport of long-chain fatty acids: evidence for a facilitated process.},
  author={Nada A. Abumrad and Charles Harmon and Azeddine Ibrahimi},
  journal={Journal of lipid research},
  volume={39 12},
In mammalian cells, membrane uptake of long-chain fatty acids is mediated by two separate components; a passive component that is a linear function of the concentration of free fatty acid in the extracellular medium and a saturable component that exhibits the characteristics of a protein-facilitated process. This review summarizes the body of work that has accumulated related to the mechanism of fatty acid transport. Evidence in support of a facilitated uptake process is presented with relation… CONTINUE READING

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