Membrane transport mechanisms of mizoribine in the rat intestine and human epithelial LS180 cells.

@article{Ishida2009MembraneTM,
  title={Membrane transport mechanisms of mizoribine in the rat intestine and human epithelial LS180 cells.},
  author={Kazuya Ishida and Mari Takaai and Ayano Yotsutani and Masato Taguchi and Yukiya Hashimoto},
  journal={Biological \& pharmaceutical bulletin},
  year={2009},
  volume={32 4},
  pages={
          741-5
        }
}
The aim of the present study was to characterize membrane transport mechanisms of mizoribine in the intestinal epithelial cells. We evaluated the contribution of Na(+)-dependent and -independent membrane transporters to mizoribine absorption in the rat intestine using an in situ closed loop method. In addition, we evaluated the effects of structurally related compounds, extracellular Na(+) concentrations, and an inhibitor of Na(+)-independent equilibrative nucleoside transporter… 

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