Membrane trafficking: Endurance of the weakest signal

  title={Membrane trafficking: Endurance of the weakest signal},
  author={Ekat A. Kritikou},
  journal={Nature Reviews Molecular Cell Biology},
MET, the Tyr kinase receptor of hepatocyte growth factor (HGF), activates diverse signalling pathways, including AKT/protein kinase B (PKB), extracellular signal-regulated kinase (ERK), Rac and signal transducer and activator of transcription-3 (STAT3). But how are these different downstream pathways specifically regulated and coordinated? Reporting in… CONTINUE READING