Membrane topology of the STT3 subunit of the oligosaccharyl transferase complex.

Abstract

The highly conserved membrane protein STT3 is part of the oligosaccharyl transferase complex in the endoplasmic reticulum of eukaryotic cells. Various experimental observations strongly suggest that STT3 contains the active site of the complex. Here, we report a detailed topology study of STT3 from two different organisms, Saccharomyces cerevisiae and mouse… (More)

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Cite this paper

@article{Kim2005MembraneTO, title={Membrane topology of the STT3 subunit of the oligosaccharyl transferase complex.}, author={Hyun Kim and Gunnar von Heijne and Ingmarie Nilsson}, journal={The Journal of biological chemistry}, year={2005}, volume={280 21}, pages={20261-7} }