Membrane targeted anticancer drugs: potent inducers of apoptosis and putative radiosensitisers.

Abstract

In the last two decades, cellular membranes have been identified as novel targets for antineoplastic drugs. Two classes of synthetic phospholipid analogues: the alkyllysophospholipids (ALP) with the prototypical 1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (Et-18-OCH3, Edelfosine), as well as the alkylphosphocholines (APC) with the prototypical… (More)

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Cite this paper

@article{Jendrossek2003MembraneTA, title={Membrane targeted anticancer drugs: potent inducers of apoptosis and putative radiosensitisers.}, author={Verena Jendrossek and Ren{\'e} Handrick}, journal={Current medicinal chemistry. Anti-cancer agents}, year={2003}, volume={3 5}, pages={343-53} }