Membrane structure and electron microscopy. The significance of physical problems and techniques (freeze etching).

@article{Zingsheim1972MembraneSA,
  title={Membrane structure and electron microscopy. The significance of physical problems and techniques (freeze etching).},
  author={H. P. Zingsheim},
  journal={Biochimica et biophysica acta},
  year={1972},
  volume={265 3},
  pages={
          339-66
        }
}
Abstract The classical methods of chemical fixation and staining are not sufficiently well understood to be very helpful in the study of the molecular structure of membranes. It was pointed out that any interpretation of electron micrographs in terms of membrane subunits must also take into account the known facts of phase contrast in the electron microscope. The possibility of misinterpretation of defocussed micrographs has been almost universally neglected in the past. Previous publications… CONTINUE READING
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Lipid Polymorphism and Membrane Function

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  • Archives of Microbiology
  • 1978
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Rotary replication for freeze-etching

  • The Journal of cell biology
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