Membrane structure, toxins and phospholipase A2 activity.

  title={Membrane structure, toxins and phospholipase A2 activity.},
  author={Leo P. Vernon and John D. Bell},
  journal={Pharmacology & therapeutics},
  volume={54 3},
The phospholipid-hydrolyzing enzyme phospholipase A2 (PLA2) (EC exists in several forms which can be located in the cytosol or on cellular membranes. We review briefly cellular regulatory mechanisms involving covalent modification by protein kinase C and the action of Ca2+, cytokines, G proteins and other cellular proteins. The major focus is the… CONTINUE READING