Membrane resistivity estimated for the purkinje neuron by means of a passive computer model

  title={Membrane resistivity estimated for the purkinje neuron by means of a passive computer model},
  author={D. Shelton},
  • D. Shelton
  • Published 1985
  • Biology, Medicine
  • Neuroscience
  • A multicompartment passive electrotonic computer model is constructed for the cerebellar Purkinje cell of the guinea-pig. The model has 1089 coupled compartments to accurately represent the morphology of the Purkinje cell. In order that the calculated behavior of the model fit the published electrophysiological observations of somatic and dendritic input conductance, the neural membrane resistivity must be spatially non-uniform. The passive electrical parameter values for which the model best… CONTINUE READING
    116 Citations

    Figures, Tables, and Topics from this paper

    Electrotonic architecture of cat gamma motoneurons.
    • 27
    • PDF
    The Composite Neuron: A Realistic One-Compartment Purkinje Cell Model Suitable for Large-Scale Neuronal Network Simulations
    • A. Coop, G. Reeke
    • Computer Science, Medicine
    • Journal of Computational Neuroscience
    • 2004
    • 8
    An active membrane model of the cerebellar Purkinje cell II. Simulation of synaptic responses.
    • 325
    • PDF
    Contribution of voltage-dependent potassium channels to the somatic shunt in neck motoneurons of the cat.
    • 21
    • PDF


    A computer model of cerebellar purkinje cells
    • 66
    • PDF
    Branching dendritic trees and motoneuron membrane resistivity.
    • W. Rall
    • Biology, Medicine
    • Experimental neurology
    • 1959
    • 871
    Time constants and electrotonic length of membrane cylinders and neurons.
    • W. Rall
    • Chemistry, Medicine
    • Biophysical journal
    • 1969
    • 632
    • PDF
    Integrative properties of crayfish medial giant neuron: steady-state model.
    • 19
    Tetrodotoxin-resistant dendritic spikes in avian Purkinje cells.
    • R. Llinás, R. Hess
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1976
    • 233
    • PDF
    Response properties and electrical constants of caudate nucleus neurons in the cat.
    • 56