Membrane-related effects underlying the biological activity of the anthraquinones emodin and barbaloin.

@article{Alves2004MembranerelatedEU,
  title={Membrane-related effects underlying the biological activity of the anthraquinones emodin and barbaloin.},
  author={Daiane S Alves and Laura P{\'e}rez-Fons and Amparo Estepa and Vicente Micol},
  journal={Biochemical pharmacology},
  year={2004},
  volume={68 3},
  pages={549-61}
}
Commercial plant extracts containing anthraquinones are being increasingly used for cosmetics, food and pharmaceuticals due to their wide therapeutic and pharmacological properties. In this work, the interaction with model membranes of two representative 1,8-dihydroxyanthraquinones, barbaloin (Aloe) and emodin (Rheum, Polygonum), has been studied in order to explain their effects in biological membranes. Emodin showed a higher affinity for phospholipid membranes than barbaloin did, and was more… CONTINUE READING

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