Membrane raft association is a determinant of plasma membrane localization.

@article{DiazRohrer2014MembraneRA,
  title={Membrane raft association is a determinant of plasma membrane localization.},
  author={Blanca B. Diaz-Rohrer and Kandice R Levental and Keith Edward Simons and Ilya Levental},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2014},
  volume={111 23},
  pages={
          8500-5
        }
}
The lipid raft hypothesis proposes lateral domains driven by preferential interactions between sterols, sphingolipids, and specific proteins as a central mechanism for the regulation of membrane structure and function; however, experimental limitations in defining raft composition and properties have prevented unequivocal demonstration of their functional relevance. Here, we establish a quantitative, functional relationship between raft association and subcellular protein sorting. By systematic… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 34 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 49 REFERENCES

Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane

  • MJ Gerl
  • J Cell Biol
  • 2012
2 Excerpts

Similar Papers

Loading similar papers…