Membrane proteins shape up: understanding in vitro folding.

@article{Booth2006MembranePS,
  title={Membrane proteins shape up: understanding in vitro folding.},
  author={Paula Booth and Paul Curnow},
  journal={Current opinion in structural biology},
  year={2006},
  volume={16 4},
  pages={
          480-8
        }
}
Progress in structural biology has begun to reveal the precise architecture of integral membrane proteins. However, the manner in which these complex structures are achieved remains unclear. Recent developments are starting to shed light on the unfolding and folding of a small but growing number of membrane proteins. Mechanistic details derived from kinetic and thermodynamic experiments now enable comparison of the folding of different membrane proteins and their water-soluble cousins. This… CONTINUE READING

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