Membrane potential regulates sea urchin sperm adenylylcyclase.

@article{Beltran1996MembranePR,
  title={Membrane potential regulates sea urchin sperm adenylylcyclase.},
  author={Carmen Beltran and Oscar Iv{\'a}n Londo{\~n}o Zapata and Alberto Darszon},
  journal={Biochemistry},
  year={1996},
  volume={35 23},
  pages={
          7591-8
        }
}
Adenylylcyclase (AC) from sea urchin sperm does not appear to be regulated by G proteins [Hildebrandt, J. D., Tash, J. S., Kirchick, H. J., Lipschunits, L., Secra, R. D., & Birmbaumer, L. (1985) Endocrinology 116, 1357-1366]. During sperm activation and the acrosome reaction, membrane potential changes and cAMP increases. Here we explore if membrane potential can modulate the sperm AC. Hyperpolarization of Lytechinus pictus sea urchin sperm either with valinomycin in artificial sea water (ASW… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 30 CITATIONS

Determining the molecular basis of voltage sensitivity in membrane proteins

  • The Journal of general physiology
  • 2018
VIEW 5 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

Iodine accumulation in sea urchin larvae is dependent on peroxide.

  • The Journal of experimental biology
  • 2013
VIEW 1 EXCERPT
HIGHLY INFLUENCED

Sperm Sensory Signaling.

  • Cold Spring Harbor perspectives in biology
  • 2017
VIEW 2 EXCERPTS
CITES BACKGROUND