Membrane potential mediates the cellular binding of nanoparticles.

@article{Shin2013MembranePM,
  title={Membrane potential mediates the cellular binding of nanoparticles.},
  author={Edwin H Shin and Ye Li and U. Saravana Kumar and Hursh V Sureka and Xianren Zhang and Christine K Payne},
  journal={Nanoscale},
  year={2013},
  volume={5 13},
  pages={5879-86}
}
The use of nanoparticles for cellular therapeutic or sensing applications requires nanoparticles to bind, or adhere, to the cell surface. While nanoparticle parameters such as size, shape, charge, and composition are important factors in cellular binding, the cell itself must also be considered. All cells have an electrical potential across the plasma membrane driven by an ion gradient. Under standard conditions the ion gradient will result in a -10 to -100 mV potential across the membrane with… CONTINUE READING
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