Membrane potential, chloride exchange, and chloride conductance in Ehrlich mouse ascites tumour cells.

@article{Hoffmann1979MembranePC,
  title={Membrane potential, chloride exchange, and chloride conductance in Ehrlich mouse ascites tumour cells.},
  author={Else Kay Hoffmann and Lars Ole Simonsen and Carsten Sj\oholm},
  journal={The Journal of physiology},
  year={1979},
  volume={296},
  pages={61-84}
}
1. The steady-state tracer exchange flux of chloride was measured at 10-150 mM external chloride concentration, substituting either lactate or sucrose for chloride. The chloride flux saturates in both cases with a K 1/2 about 50 and 15 mM, respectively. 2. The inhibitory effect of other monovalent anions on the chloride transport was investigated by measuring the 36Cl- efflux into media where either bromide, nitrate, or thiocyanate had been substituted for part of the chloride. The sequence of… CONTINUE READING