Membrane phospholipid redistribution in cancer micro-particles and implications in the recruitment of cationic protein factors

@inproceedings{Hou2014MembranePR,
  title={Membrane phospholipid redistribution in cancer micro-particles and implications in the recruitment of cationic protein factors},
  author={Songwang Hou and Doris Grillo and Carol L. Williams and John Andrew Wasserstrom and Igal Szleifer and Mingming Zhao},
  booktitle={Journal of extracellular vesicles},
  year={2014}
}
Cancer cell-derived micro-particles (MPs) play important regulatory roles on cellular and system levels. These activities are attributed in part to protein factors carried by MPs. However, recruitment strategies for sequestering certain protein factors in MPs are poorly understood. In the current study, using exogenous and endogenously expressed phospholipid-binding probes, we investigated the distribution of membrane phospholipids in MPs as a potential mechanism for electrostatically enriching… CONTINUE READING

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