Membrane microdomain formation is crucial in epiboly during gastrulation of medaka.


Membrane microdomain (microdomain) was isolated from early gastrula embryos. The isolated microdomain was characterized by enrichment of cholesterol and sphingomyelin, and by the presence of huge glycoproteins containing Lewis X structure. Importance of the microdomain in the progress of epiboly was assessed using methyl beta-cyclodextrin (MBCD) and C2… (More)