Membrane-localized extra-large G proteins and Gbg of the heterotrimeric G proteins form functional complexes engaged in plant immunity in Arabidopsis.

@article{Maruta2015MembranelocalizedEG,
  title={Membrane-localized extra-large G proteins and Gbg of the heterotrimeric G proteins form functional complexes engaged in plant immunity in Arabidopsis.},
  author={Natsumi Maruta and Yuri Trusov and Eric Brenya and Urvi B. Parekh and Jos{\'e} Ram{\'o}n Botella},
  journal={Plant physiology},
  year={2015},
  volume={167 3},
  pages={1004-16}
}
In animals, heterotrimeric G proteins, comprising Ga, Gb, and Gg subunits, are molecular switches whose function tightly depends on Ga and Gbg interaction. Intriguingly, in Arabidopsis (Arabidopsis thaliana), multiple defense responses involve Gbg, but not Ga. We report here that the Gbg dimer directly partners with extra-large G proteins (XLGs) to mediate plant immunity. Arabidopsis mutants deficient in XLGs, Gb, and Gg are similarly compromised in several pathogen defense responses, including… CONTINUE READING
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