Membrane lipid peroxidation by the peroxidase-like activity of magnetite nanoparticles.

  title={Membrane lipid peroxidation by the peroxidase-like activity of magnetite nanoparticles.},
  author={Lijun Wang and Yue Min and Doudou Xu and Fengjiao Yu and Wuzong Zhou and Alfred Cuschieri},
  journal={Chemical communications},
  volume={50 76},
We report that Fe3O4 nanoparticles are able to catalyse lipid peroxidation in liposomes at acidic but not neutral pH. The oxidation is dependent on either pre-existing lipid peroxides or hydrogen peroxide as a substrate. This is the first evidence for metal oxide nanoparticles as peroxidase mimetics oxidising biomolecules in a relevant environment. 

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