Membrane fusion activity of purified SipB, a Salmonella surface protein essential for mammalian cell invasion.

@article{Hayward2000MembraneFA,
  title={Membrane fusion activity of purified SipB, a Salmonella surface protein essential for mammalian cell invasion.},
  author={Richard D Hayward and Emma J. McGhie and Vassilis Koronakis},
  journal={Molecular microbiology},
  year={2000},
  volume={37 4},
  pages={727-39}
}
An early event in Salmonella infection is the invasion of non-phagocytic intestinal epithelial cells. The pathogen is taken up by macropinocytosis, induced by contact-dependent delivery of bacterial proteins that subvert signalling pathways and promote cytoskeletal rearrangement. SipB, a Salmonella protein required for delivery and invasion, was shown to… CONTINUE READING