Membrane flow within the myelin sheath in IDPN neuropathy.

  title={Membrane flow within the myelin sheath in IDPN neuropathy.},
  author={A. E. Blaurock and M B Genter St Clair and Dorothy Graham},
  journal={Neuropathology and applied neurobiology},
  volume={17 4},
This report describes some aspects of beta,beta'-iminodipropionitrile (IDPN) neuropathy in rats as observed by ultrastructural methods and X-ray diffraction. Light microscopy shows gross swelling of the axons in proximal lumbar spinal roots 8 days after intraperitoneal injection of IDPN. Mean axon cross-sectional area and mean axon perimeter increased to 280% and 160% of their control values, respectively. At the same time, myelin membrane packing was not visibly disturbed. In addition, X-ray… CONTINUE READING

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