Membrane estrogen receptors: genomic actions and post transcriptional regulation.

@article{Jacob2006MembraneER,
  title={Membrane estrogen receptors: genomic actions and post transcriptional regulation.},
  author={Julie Jacob and Kelly Sebastian and Sony Devassy and Lakshmi Priyadarsini and Mohamed Febin Farook and A. Mohamed Shameem and Deepa Elizabeth Mathew and Sreeharshan Sreeja and Raghava Varman Thampan},
  journal={Molecular and cellular endocrinology},
  year={2006},
  volume={246 1-2},
  pages={34-41}
}
The primary cellular location of the nuclear estrogen receptor II (nER II) is the plasma membrane. A number of reports that have appeared in the recent past indicate that plasma membrane localized estrogen receptor alpha (ERalpha) also exists. Whether the membrane localized ERalpha represents the receptor that binds to the estrogen responsive element (ERE) remains to be known. The mechanisms that underlie the internalization of nER II (non-activated estrogen receptor, deglycosylated) have been… CONTINUE READING