Membrane dynamics and interactions in measles virus dendritic cell infections.

@article{Avota2013MembraneDA,
  title={Membrane dynamics and interactions in measles virus dendritic cell infections.},
  author={Elita Avota and Susanne Koethe and Sibylle Schneider-Schaulies},
  journal={Cellular microbiology},
  year={2013},
  volume={15 2},
  pages={161-9}
}
Viral entry, compartmentalization and transmission depend on the formation of membrane lipid/protein microdomains concentrating receptors and signalosomes. Dendritic cells (DCs) are prime targets for measles virus (MV) infection, and this interaction promotes immune activation and generalized immunosuppression, yet also MV transport to secondary lymphatics where transmission to T cells occurs. In addition to MV trapping, DC-SIGN interaction can enhance MV uptake by activating cellular… CONTINUE READING