Membrane dynamic alterations associated with activation of human platelets by thrombin.

@article{Nathan1980MembraneDA,
  title={Membrane dynamic alterations associated with activation of human platelets by thrombin.},
  author={Ilana Nathan and Gary R. Fleisher and Alexander Dvilansky and Avinoam A. Livne and Abraham H. Parola},
  journal={Biochimica et biophysica acta},
  year={1980},
  volume={598 2},
  pages={417-21}
}
Two fluorescent probes, N-carboxymethylisatoic anhydride, which binds to membrane proteins, and 1,6-diphenyl-1,3,5-hexatriene, a lipophilic label, have been used to follow membrane microenvironmental changes. Activation of human platelets by thrombin resulted in a simultaneous increase in values of fluorescence polarization (P) of both probes during the… CONTINUE READING