Membrane dielectric changes indicate induced apoptosis in HL-60 cells more sensitively than surface phosphatidylserine expression or DNA fragmentation.

@article{Wang2002MembraneDC,
  title={Membrane dielectric changes indicate induced apoptosis in HL-60 cells more sensitively than surface phosphatidylserine expression or DNA fragmentation.},
  author={Xujing Wang and Frederick F. Becker and Peter R. C. Gascoyne},
  journal={Biochimica et biophysica acta},
  year={2002},
  volume={1564 2},
  pages={412-20}
}
The specific membrane capacitance and conductivity of mammalian cells, which reflect their surface morphological complexities and membrane barrier functions, respectively, have been shown to respond to cell physiologic and pathologic changes. Here, the effects of induced apoptosis on these membrane properties of cultured human promyelocytic HL-60 cells are reported. Changes in membrane capacitance and conductivity were deduced from measurements of cellular dielectrophoretic crossover… CONTINUE READING
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